Dofatrim-Ject (Trimethoprim Sulphate)

This treatment applies to the following species:
Beef Cattle, Dairy Cattle, Swine, Veal

Sterile Antibacterial Injectable Solution
Veterinary Use Only
Din 02285495

Each Ml Contains

Active Ingredients:
Trimethoprim 40 mg
Sulfadoxine 200 mg

Methyl parahydroxybenzoate 1 mg
Propylene glycol 0.1 mL

Dofatrim-ject is indicated in cattle for the treatment of:

  • respiratory tract infections: bacterial pneumonias including bovine pneumonic pasteurellosis (shipping fever);
  • alimentary tract infections: primarily enteric and septicaemic colibacillosis and salmonellosis;
  • other infections: infectious pododermatitis (foot rot, foul in the foot) and septicaemias.

Dofatrim-ject is indicated in swine for the treatment of:

  • respiratory tract infections: bacterial pneumonias;
  • alimentary tract infections: colibacillosis and post-weaning scours;
  • other infections: metritis-mastitis-agalactia syndrome of sows (MMA) and bacterial arthritis.

Sensitive organisms (in vitro) are: Clostridium spp., Corynebacterium spp., Escherichia coli, Haemophilus in"uenzae, Klebsiella spp., Pasteurella spp., Salmonella spp., Staphylococcus aureus including penicillinase producing organisms and Streptococcus spp.

Dofatrim-ject Dosage And Administration

Dofatrim-ject should be administered at a dose rate of 16 mg per kg of body weight (1 mL/15 kg BW) daily for 3 to 5 days. Intramuscular injection is recommended for cattle and pigs, but if a particularly rapid response is required in acute infections Dofatrim-ject can be administered by slow intravenous injection.

Dofatrim-ject Cautions

For piglets weighing less than 4.5 kg, do not exceed 0.5 mL.
Not more than 20 ml should be injected per site.
Inject slowly for intravenous administration.
Following intramuscular injection, local pain and swelling can occur. The lesions on and around the site of intramuscular injection may persist beyond the slaughter withholding period of 10 days.
With intravenous therapy generally, and sulfonamides in particular, hypersensitivity reactions can occur and should be appropriately treated with corticosteroids or epinephrine.


The use of Dofatrim-ject is contra-indicated in animals with severe renal or hepatic insuficiency.
Dofatrim-ject should not be used in cattle or pigs showing marked liver parenchymal damage, in animals with blood dyscrasia, nor in those with a history of sulfonamide sensitivity.


Treated animals must not be slaughtered for use in food for at least 10 days after the latest treatment with this drug. Milk taken from treated animals within 96 hours after the latest treatment must not be used as food.

Keep out of reach of children.


Dofatrim-ject should he stored in a cool place (8°C - 15°C).


100 or 250 mL vials.